Cardiovascular Health
At a glance
- Cardiovascular health is closely linked to metabolic and vascular health
- Carbohydrate quality influences postprandial blood glucose and insulin responses
- Isomaltulose provides a lower and more sustained blood glucose response
- Human studies have reported beneficial effects on vascular function and arterial stiffness in specific populations
- Replacing sucrose with isomaltulose has shown neutral or beneficial effects on blood lipid parameters
Explore further:
The role of carbohydrate quality
Vascular function and arterial health
Incretin response and metabolic signaling
Lipid metabolism and cardiometabolic risk
Conclusion
Cardiovascular health is closely connected to metabolic and vascular health. Compared with rapidly available carbohydrates, isomaltulose provides lower postprandial blood glucose and insulin responses, while human studies have also reported beneficial effects on vascular function, arterial stiffness, and selected blood lipid parameters in specific populations
References
Brunner S, Holub I, Theis S, Gostner A, Melcher R, Wolf P, Amann-Gassner U, Scheppach W, Hauner H (2012) Metabolic Effects of Replacing Sucrose by Isomaltulose in Subjects With Type 2 Diabetes: A randomized double-blind trial. Diabetes Care 35(6):1249-1251.
de Groot E, Schweitzer L, Theis S (2020) Efficacy of isomaltulose compared to sucrose in modulating endothelial function in overweight adults. Nutrients 12(1):141.
Holub I, Gostner A, Theis S et al. (2010) Novel findings on the metabolic effects of the low glycaemic carbohydrate isomaltulose (Palatinose™). Br J Nutr 103(12):1730-1737.
Keller J, Kahlhöfer J, Peter A et al. (2016) Effects of low versus high glycemic index sugar-sweetened beverages on postprandial vasodilatation and inactivity-induced impairment of glucose metabolism in healthy men. Nutrients 8(12):802.
Kobayashi R, Sakazaki M, Nagai Y et al. (2023) Habitual isomaltulose intake reduces arterial stiffness associated with postprandial hyperglycemia in middle-aged and elderly people: a randomized controlled trial. Heart and Vessels 39(2):123-134.
Pfeiffer AFH, Keyhani-Nejad F (2018) High glycemic index metabolic damage: a pivotal role of GIP and GLP-1. Trends in Endocrinology and Metabolism 29(5):289-299.